Code
FSG-PFMP-01AX
Test
Active-Compendium
88377x1 manual or 88374x1 automated
Clinical
Pathology
Bone Marrow Aspirate: N/A
Peripheral Blood: N/A
Fresh, Unfixed Tissue: N/A
Paraffin Block: H&E slide (required) plus paraffin block.
Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns.
Note: Specimen must contain villi and/or fetal tissue.
Peripheral Blood: N/A
Fresh, Unfixed Tissue: N/A
Paraffin Block: H&E slide (required) plus paraffin block.
Cut Slides: H&E slide (required) plus 4 unstained slides cut at 4-5 microns.
Note: Specimen must contain villi and/or fetal tissue.
Flag Active
True
Orderable Test Description
<p>Ploidy FISH (Centromeres 1 and 11) with p57 IHC.<br><br>
Ploidy FISH analyzes chromosomal centromeres 1 and 11 to assess ploidy status, aiding in the distinction between triploidy (commonly associated with partial mole) and diploidy (commonly associated with complete mole).<br><br>
<b>FISH Probes:</b><br>
* Centromere 1 (1p11.1–q11.1)<br>
* Centromere 11 (11q12)<br><br>
<b>Associated IHC Antibody Marker:</b><br>
p57<br><br>
<b>Clinical Indications:</b><br>
* Complete molar pregnancy<br>
* Partial molar pregnancy<br>
* Abortus with hydropic changes<br><br>
<b>Service level:</b><br>
This test is available on a consult basis only.</p>
Ploidy FISH analyzes chromosomal centromeres 1 and 11 to assess ploidy status, aiding in the distinction between triploidy (commonly associated with partial mole) and diploidy (commonly associated with complete mole).<br><br>
<b>FISH Probes:</b><br>
* Centromere 1 (1p11.1–q11.1)<br>
* Centromere 11 (11q12)<br><br>
<b>Associated IHC Antibody Marker:</b><br>
p57<br><br>
<b>Clinical Indications:</b><br>
* Complete molar pregnancy<br>
* Partial molar pregnancy<br>
* Abortus with hydropic changes<br><br>
<b>Service level:</b><br>
This test is available on a consult basis only.</p>
Orderable Turn Around Time
3-5 Days
Keywords
Orderable Biomarkers
NY Approved
True
Orderable Biomarkers JSON
{"Fluorescence In Situ Hybridization (FISH)": {"Polyploidy": ["Centromere 1", "Centromere 11"]}}
Keywords string
CEN 1/CEN 11, CEN1, CEP1, CEN 11, CEP 11, hydatidiform, tetraploidy, mosaicism Ploidy FISH for Molar Pregnancy
Title URL
ploidy-fish-for-molar-pregnancy
Storage and transportation
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of Collection.